column_name,type,required,allowed_values,description,example  
record_id,string,yes,AFS-0001 format,Stable unique row identifier,AFS-0001  
taxon_scope,string,yes,General Archaea|Euryarchaeota|Haloarchaea|Other,Taxonomic scope of claim,General Archaea  
organism_example,string,yes,free text,Representative organism or taxa label,Haloferax volcanii  
substrate_class,string,yes,free text,Class of protein substrate,Secretory precursors  
substrate_example,string,yes,free text,Representative substrate example,S-layer glycoprotein  
targeting_route,string,yes,Cytosolic|Sec|Tat|Sec-like|Sec/Tat|Cytosolic/Sec/Tat|Unknown,Primary trafficking route,Sec  
folding_module,string,yes,free text,Dominant folding system or context,Thermosome  
protease_or_processing_enzyme,string,yes,None|Signal peptidase I|Prepilin peptidase-like enzyme|ArtA|ArtA family|Archaeosortase family|Unknown|SPI/TFPP-like/ArtA,Primary maturation enzyme class,Signal peptidase I  
cleavage_polarity,string,yes,N-terminus|C-terminus|Internal|None|N-terminus/C-terminus,Cleavage orientation if present,N-terminus  
processing_site_context,string,yes,free text,Subcellular processing context,Membrane cleavage during export  
coupled_modification,string,yes,free text,Modification coupled to cleavage/processing,Signal peptide removal  
post_processing_destination,string,yes,free text,Final substrate destination,Surface display  
cellular_zone,string,yes,Cytosol|Membrane|Surface|Membrane/Surface|Cytosol/Membrane/Surface,Primary zone of maturation outcome,Membrane  
readout_signature,string,yes,free text,Expected experimental signature,Lower apparent MW after leader removal  
evidence_level,string,yes,Review|Primary,Evidence class for row-level claim,Review  
citation_key,string,yes,key in citation_map.csv,Reference mapping key,SPI_ARCHAEA_2007  
confidence_tier,string,yes,Foundational|Intermediate|Advanced,Curation confidence tier,Intermediate  
curation_status,string,yes,stable|provisional|revised,Curation lifecycle status,stable  
